22.4 Fatty Acids are Synthesized and Degraded by Different Pathways

Fatty Acid Synthesis Consists of a Series of Condensation, Reduction, Dehydration, and Reduction Reactions

D rather than L isomer is formed in fatty acid synthesis.

NADPH is consumed in biosynthetic reactions, while NADH is generated in energy-yielding reactions

Thioesterase hydrolyses C16-acyl ACP to yield palmitate and ACP

Elongation by fatty acid synthase complex stops on the formation of palmitate (c16)

Several Sources Supply NADPH for Fatty Acid synthesis

Draw reaction mechanisms for Figure 22.27 p.639 (Reaction equations help)

Understand Pathway Integration for Fatty Acid Synth

Read chapter on Pentose Phosphate Pathway